CHILLICOTHE, MO 64601 Weather Forecast & Current Conditions

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CHILLICOTHE, MO
Current Weather

10:51 AM CDT MAY 21, 2026
57°F
Feels Like: 56°F
Dewpoint: 48°F
Rel. Hum.: 72%
Visibility:
Wind: Variable at 6 mph
Pressure: 30.19 inches
Last 72 hours

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CHILLICOTHE, MO 64601
Weather Forecast

Snowfall Forecast pages
Snow Depth pages
TODAY
Mostly cloudy. A slight chance of showers this morning. Highs in the mid 60s. East winds 5 to 10 mph. Chance of rain 20 percent.
TONIGHT
Cloudy. A slight chance of showers in the evening, then a chance of showers after midnight. Lows in the lower 50s. East winds 5 to 10 mph. Chance of rain 40 percent.
FRIDAY
Mostly cloudy with a 50 percent chance of showers. Highs in the upper 60s. East winds 5 to 10 mph.
FRIDAY NIGHT
Mostly cloudy. Lows in the lower 50s. East winds 5 to 10 mph, becoming southeast after midnight.
SATURDAY
Partly sunny. Highs in the mid 70s. West winds around 5 mph.
SATURDAY NIGHT
Mostly cloudy. Lows in the mid 50s.
SUNDAY
Mostly sunny. Highs in the upper 70s.
SUNDAY NIGHT
Partly cloudy in the evening, then becoming mostly clear. Lows in the mid 50s.
MEMORIAL DAY AND MONDAY NIGHT
Partly cloudy. Highs in the lower 80s. Lows around 60.
TUESDAY
Partly sunny. A chance of showers and thunderstorms in the afternoon. Highs in the lower 80s. Chance of rain 40 percent.
TUESDAY NIGHT
Mostly cloudy in the evening, then partly cloudy with a chance of showers and thunderstorms after midnight. Lows in the lower 60s. Chance of rain 40 percent.
WEDNESDAY
Partly sunny. A chance of showers and thunderstorms in the afternoon. Highs in the mid 80s. Chance of rain 50 percent.

Visible Weather Satellite
CHILLICOTHE, MO 64601
Infrared Weather Satellite
CHILLICOTHE, MO 64601
NEXRAD Weather Radar
CHILLICOTHE, MO 64601

CHILLICOTHE, MO 3 hourly weather forecast

weather forecast created  7:00 AM CDT  5/21/2026
Thursday
21 MAY 2026
CHILLICOTHE, MO 64601 weather forecast Day 1, 12 hours 1 PM 59° 58° Mostly Cloudy 5%

0% Thunder
( 4% severe)
E   8 69% 49°
High 64° CHILLICOTHE, MO 64601 weather forecast Day 1, 15 hours 4 PM 63° 63° Mostly Cloudy ENE   8 62% 50°
Mostly Cloudy



CHILLICOTHE, MO 64601 weather forecast Day 1, 18 hours 7 PM 63° 63° Mostly Cloudy 12%
RAIN
.1–.25 in
0% Thunder
( 5% severe)
E   7 65% 51°
CHILLICOTHE, MO 64601 weather forecast Day 1, 21 hours 10 PM 60° 60° Mostly Cloudy E   6 75% 52°
Friday
22 MAY 2026
CHILLICOTHE, MO 64601 weather forecast Day 2, 0 hours 1 AM 58° 57° Mostly Cloudy 38%
RAIN
.5–1 in
0% Thunder
( 11% severe)
E   6 77% 51°
Low 53° CHILLICOTHE, MO 64601 weather forecast Day 2, 3 hours 4 AM 56° 55° Mostly Cloudy E   6 86% 52°
High 68° CHILLICOTHE, MO 64601 weather forecast Day 2, 6 hours 7 AM 56° 54° Mostly Cloudy 34%
RAIN
>2 in
0% Thunder
( 7% severe)
E   7 86% 52°

Mostly Cloudy

Chance of Rain

CHILLICOTHE, MO 64601 weather forecast Day 2, 9 hours 10 AM 59° 58° Mostly Cloudy E   8 83% 54°
CHILLICOTHE, MO 64601 weather forecast Day 2, 12 hours 1 PM 63° 63° Mostly Cloudy 20%
RAIN
.1–.25 in
0% Thunder
( 7% severe)
E   8 81% 57°
CHILLICOTHE, MO 64601 weather forecast Day 2, 15 hours 4 PM 66° 66° Mostly Cloudy E   7 75% 58°
CHILLICOTHE, MO 64601 weather forecast Day 2, 18 hours 7 PM 67° 67° Mostly Cloudy 3%

0% Thunder
( 6% severe)
ESE   5 70% 57°
CHILLICOTHE, MO 64601 weather forecast Day 2, 21 hours 10 PM 62° 63° Mostly Cloudy   CALM 84% 57°
Saturday
23 MAY 2026
CHILLICOTHE, MO 64601 weather forecast Day 3, 0 hours 1 AM 59° 60° Mostly Cloudy 8%

0% Thunder
( 6% severe)
  CALM 87% 55°
Low 54° CHILLICOTHE, MO 64601 weather forecast Day 3, 3 hours 4 AM 57° 58° Mostly Cloudy   CALM 96% 56°
High 76° CHILLICOTHE, MO 64601 weather forecast Day 3, 6 hours 7 AM 58° 59° Mostly Cloudy 3%

0% Thunder
( 11% severe)
  CALM 96% 57°

Mostly Cloudy



CHILLICOTHE, MO 64601 weather forecast Day 3, 9 hours 10 AM 67° 67° Mostly Cloudy   CALM 75% 59°
CHILLICOTHE, MO 64601 weather forecast Day 3, 15 hours 1 PM 72° 72° Partly Cloudy 9%

0% Thunder
( 26% severe)
WNW   5 66% 60°
CHILLICOTHE, MO 64601 weather forecast Day 3, 18 hours 4 PM 75° 75° Partly Cloudy WNW   5 58% 59°
CHILLICOTHE, MO 64601 weather forecast Day 3, 21 hours 7 PM 73° 73° Mostly Cloudy     NW   1 59% 58°

CHILLICOTHE, MO extended weather forecast

Sunday
24 MAY 2026
Monday
25 MAY 2026
Tuesday
26 MAY 2026
Wednesday
27 MAY 2026
Thursday
28 MAY 2026
Low 59° Low 63° Low 64° Low 63° Low 64°
High 82° High 83° High 80° High 79° High 82°
CHILLICOTHE, MO 64601 weather forecast Day 4 CHILLICOTHE, MO 64601 weather forecast Day 5 CHILLICOTHE, MO 64601 weather forecast Day 6 CHILLICOTHE, MO 64601 weather forecast Day 7 <!--SEARCHED_TOWN_NAME--> weather forecast Day 8
Mostly Cloudy
37% Rain
Partly Cloudy
25% Rain
Overcast
38% Rain
Overcast
67% Rain
Overcast
48% Rain
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